Research workbench

IL-1RAPL2 TIR domain

Analyse IL-1RAPL2 TIR domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7FD3
Type: protein
Length: 155 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.99
Source: Homo sapiens
Molecule: X-linked interleukin-1 receptor accessory protein-like 2
EC: 3.2.2.6
UniProt: Q9NP60
Pockets: 1 · best druggability 0.49

Structure

x-ray diffraction · resolution 2.99 · 1 distinct chain · 46% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	X-linked interleukin-1 receptor accessory protein-like 2 (EC 3.2.2.6)	protein	155	46% helix, 16% strand	Q9NP60

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	164	0.49	0.77	19	empty

Compared structures

7FD3 · Il-1RAPL2 tir domain · the same entry in another collection · chain A against A, TM-score 1.00
Q9NP60 · AlphaFold monomer V2.0 prediction for X-linked interleukin-1 receptor accessory… · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9NP60
Elsewhere: RCSB PDB 7FD3 · PDBe 7FD3 · UniProt Q9NP60

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