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Crystal structure of arginine kinase (AK3) from the ciliate Paramecium tetraurelia

Analyse Crystal structure of arginine kinase (AK3) from the ciliate Paramecium… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 7EWS
Type: protein
Length: 756 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2
Source: Paramecium tetraurelia
Molecule: arginine kinase
UniProt: A0C7I4
Pockets: 8 · best druggability 0.74

Structure

x-ray diffraction · resolution 2 · 1 distinct chain · 41% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	arginine kinase	protein	378	41% helix, 17% strand	A0C7I4

Pockets

8 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	685	0.74	0.80	55	empty
2	252	0.69	0.85	32	empty
3	447	0.69	0.81	38	empty
4	289	0.64	0.81	25	empty
5	142	0.53	0.80	32	empty

Interfaces

1 interface between chains.

A–B · 1028 Å² buried · 10 hydrogen bonds · protein-protein

Compared structures

7EWS · Crystal structure of arginine kinase (AK3) from the ciliate paramecium tetraurelia · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt A0C7I4
Elsewhere: RCSB PDB 7EWS · PDBe 7EWS · UniProt A0C7I4

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