Research workbench
ChlB3 [Aceyltransferase]
Analyse ChlB3 [Aceyltransferase] in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7EQI
- Type
- protein
- Length
- 2,647 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 3.1
- Source
- Streptomyces antibioticus
- Molecule
- ChlB3
- UniProt
- Q0R4P5
- Pockets
- 20 · best druggability 0.81
Structure
x-ray diffraction · resolution 3.1 · 8 distinct chains · 40% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | ChlB3 | protein | 334 | 40% helix, 23% strand | Q0R4P5 |
| B | ChlB3 | protein | 335 | 41% helix, 22% strand | Q0R4P5 |
| C | ChlB3 | protein | 333 | 40% helix, 22% strand | Q0R4P5 |
| D | ChlB3 | protein | 329 | 40% helix, 23% strand | Q0R4P5 |
| E | ChlB3 | protein | 332 | 40% helix, 23% strand | Q0R4P5 |
| F | ChlB3 | protein | 329 | 39% helix, 23% strand | Q0R4P5 |
| G | ChlB3 | protein | 328 | 41% helix, 23% strand | Q0R4P5 |
| H | ChlB3 | protein | 327 | 40% helix, 24% strand | Q0R4P5 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 759 | 0.81 | 0.84 | 108 | empty |
| 2 | 179 | 0.81 | 0.96 | 29 | empty |
| 3 | 180 | 0.80 | 0.96 | 28 | empty |
| 4 | 186 | 0.80 | 0.95 | 29 | empty |
| 5 | 177 | 0.80 | 0.95 | 28 | empty |
Interfaces
7 interfaces between chains.
- C–D · 2662 Ų buried · 37 hydrogen bonds · protein-protein
- A–B · 2586 Ų buried · 33 hydrogen bonds · protein-protein
- G–H · 2537 Ų buried · 32 hydrogen bonds · protein-protein
- E–F · 2498 Ų buried · 35 hydrogen bonds · protein-protein
- A–G · 626 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
- 7EQI · CHLB3 [aceyltransferase] · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q0R4P5
- Elsewhere: RCSB PDB 7EQI · PDBe 7EQI · UniProt Q0R4P5
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