Research workbench
Structure of a novel beta-mannanase BaMan113A with mannobiose, N236Y mutation.
Analyse Structure of a novel beta-mannanase BaMan113A with mannobiose, N236Y mutation. in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7DW8
- Type
- protein
- Length
- 637 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.9
- Source
- Bacillus sp. N16-5
- Molecule
- Endo-beta-1,4-mannanase
- UniProt
- A0A140EH91
- Ligands
- BMA
- Pockets
- 3 · best druggability 0.71
Structure
x-ray diffraction · resolution 1.9 · 2 distinct chains · 41% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Endo-beta-1,4-mannanase | protein | 323 | 40% helix, 20% strand | A0A140EH91 |
| B | Endo-beta-1,4-mannanase | protein | 314 | 41% helix, 20% strand | A0A140EH91 |
Ligands and binding sites
- BMA · beta-D-mannopyranose · sugar · 4 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 683 | 0.71 | 0.78 | 81 | BMA |
| 2 | 58 | 0.38 | 0.80 | 11 | empty |
| 3 | 63 | 0.37 | 0.79 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 1015 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 7DW8 · Structure of a novel beta-mannanase BAMAN113A with mannobiose, N236Y mutation. · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A0A140EH91
- Elsewhere: RCSB PDB 7DW8 · PDBe 7DW8 · UniProt A0A140EH91
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