Research workbench
Drosophila melanogaster TRAPPIII partial complex: core plus C8 and C11 attached region
Analyse Drosophila melanogaster TRAPPIII partial complex: core plus C8 and C11 attached… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 7B6R
- Type
- protein
- Length
- 2,173 residues
- Chains
- 10
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 5.8
- Source
- Drosophila melanogaster
- Molecule
- FI18195p1; Trafficking protein particle complex subunit 11; Trafficking protein particle…
- UniProt
- Q9VW22, Q8IRE3, Q9VSY8, Q9VF82, Q9VA95, Q9VLI9, Q9VUZ1, Q7K2Q8, A1Z8I0
- Pockets
- 20 · best druggability 0.84
Structure
electron microscopy · resolution 5.8 · 10 distinct chains · 48% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | FI18195p1 | protein | 269 | 77% helix, 0% strand | Q9VW22 |
| B | Trafficking protein particle complex subunit 11 | protein | 614 | 56% helix, 4% strand | Q8IRE3 |
| C | Trafficking protein particle complex subunit | protein | 165 | 44% helix, 17% strand | Q9VSY8 |
| D | GEO08327p1 | protein | 151 | 33% helix, 11% strand | Q9VF82 |
| E | Trafficking protein particle complex subunit | protein | 145 | 34% helix, 19% strand | Q9VA95 |
| F | Trafficking protein particle complex subunit | protein | 219 | 24% helix, 23% strand | Q9VLI9 |
| G | Probable trafficking protein particle complex subunit 2 | protein | 139 | 42% helix, 20% strand | Q9VUZ1 |
| H | Trafficking protein particle complex subunit 5 | protein | 164 | 55% helix, 13% strand | Q7K2Q8 |
| I | Trafficking protein particle complex subunit | protein | 169 | 43% helix, 13% strand | Q9VSY8 |
| J | TRAPPC2L | protein | 138 | 36% helix, 28% strand | A1Z8I0 |
Pockets
20 pockets found on a 1 Å grid, 20 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 420 | 0.84 | 0.92 | 70 | empty |
| 2 | 159 | 0.83 | 0.98 | 29 | empty |
| 3 | 315 | 0.80 | 0.90 | 58 | empty |
| 4 | 182 | 0.77 | 0.92 | 43 | empty |
| 5 | 90 | 0.74 | 0.96 | 17 | empty |
Interfaces
16 interfaces between chains.
- E–F · 1753 Ų buried · 38 hydrogen bonds · protein-protein
- H–I · 1244 Ų buried · 10 hydrogen bonds · protein-protein
- C–D · 1094 Ų buried · 6 hydrogen bonds · protein-protein
- D–J · 1045 Ų buried · 14 hydrogen bonds · protein-protein
- F–I · 896 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 7B6R · Drosophila melanogaster trappiii partial complex: core plus C8 and C11 attached region · the same entry in another collection · chain J against J, TM-score 1.00
- Q9VUZ1 · AlphaFold monomer V2.0 prediction for probable trafficking protein particle complex… · a predicted model of the same protein · chain G against A, TM-score 0.90
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9VW22
- Every structure of UniProt Q8IRE3
- Every structure of UniProt Q9VSY8
- Every structure of UniProt Q9VF82
- Every structure of UniProt Q9VA95
- Every structure of UniProt Q9VLI9
- Every structure of UniProt Q9VUZ1
- Every structure of UniProt Q7K2Q8
- Every structure of UniProt A1Z8I0
- Elsewhere: RCSB PDB 7B6R · PDBe 7B6R · UniProt Q9VW22 · UniProt Q8IRE3 · UniProt Q9VSY8 · UniProt Q9VF82 · UniProt Q9VA95 · UniProt Q9VLI9 · UniProt Q9VUZ1 · UniProt Q7K2Q8 · UniProt A1Z8I0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.