Research workbench
E. coli cysteine desulfurase SufS H123A with a Cys-ketimine intermediate
Analyse E. coli cysteine desulfurase SufS H123A with a Cys-ketimine intermediate in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6O13
- Type
- protein
- Length
- 405 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.203
- Source
- Escherichia coli (strain K12)
- Molecule
- Cysteine desulfurase
- EC
- 2.8.1.7, 4.4.1.16
- UniProt
- P77444
- Ligands
- CKT, CL
- Pockets
- 2 · best druggability 0.57
Structure
x-ray diffraction · resolution 2.203 · 1 distinct chain · 44% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Cysteine desulfurase (EC 2.8.1.7, 4.4.1.16) | protein | 405 | 44% helix, 19% strand | P77444 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 139 | 0.57 | 0.83 | 27 | empty |
| 2 | 145 | 0.50 | 0.79 | 25 | CKT |
Compared structures
- 6O13 · E. COLI cysteine desulfurase sufs H123A with a cys-ketimine intermediate · the same entry in another collection · chain A against A, TM-score 1.00
- P77444 · AlphaFold monomer V2.0 prediction for cysteine desulfurase (P77444) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P77444
- Elsewhere: RCSB PDB 6O13 · PDBe 6O13 · UniProt P77444
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