Research workbench
Neutralization mechanism of a monoclonal antibody targeting a porcine circovirus type 2 Cap protein conformational epitope
Analyse Neutralization mechanism of a monoclonal antibody targeting a porcine… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6LM3
- Type
- protein
- Length
- 190 residues
- Chains
- 1
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 6.7
- Source
- Porcine circovirus 2
- Molecule
- Capsid protein
- UniProt
- F5A4Z4
- Pockets
- 4 · best druggability 0.78
Structure
electron microscopy · resolution 6.7 · 1 distinct chain · 4% helix, 25% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Capsid protein | protein | 190 | 4% helix, 25% strand | F5A4Z4 |
Pockets
4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 277 | 0.78 | 0.90 | 46 | empty |
| 2 | 532 | 0.77 | 0.84 | 62 | empty |
| 3 | 61 | 0.65 | 0.93 | 18 | empty |
| 4 | 55 | 0.32 | 0.76 | 14 | empty |
Compared structures
- 6LM3 · Neutralization mechanism of a monoclonal antibody targeting a porcine circovirus type 2… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt F5A4Z4
- Elsewhere: RCSB PDB 6LM3 · PDBe 6LM3 · UniProt F5A4Z4
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