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Crystal structure of Lpg0189

Analyse Crystal structure of Lpg0189 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6L6H
Type: protein
Length: 528 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.403
Source: Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 /…
Molecule: Uncharacterized protein Lpg0189
UniProt: Q5ZZ22
Pockets: 4 · best druggability 0.69

Structure

x-ray diffraction · resolution 2.403 · 1 distinct chain · 28% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Uncharacterized protein Lpg0189	protein	264	28% helix, 35% strand	Q5ZZ22

Ligands and binding sites

GOL · Glycerol · additive · chains A
ACT · Acetate ion · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	469	0.69	0.80	62	empty
2	457	0.66	0.79	48	empty
3	66	0.62	0.91	22	empty
4	62	0.38	0.79	16	empty

Interfaces

1 interface between chains.

A–B · 1359 Å² buried · 25 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

6L6H · Crystal structure of LPG0189 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5ZZ22
Elsewhere: RCSB PDB 6L6H · PDBe 6L6H · UniProt Q5ZZ22

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