Research workbench
Crystal structure of SeMet_Lpg0189
Analyse Crystal structure of SeMet_Lpg0189 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6L6G
- Type
- protein
- Length
- 528 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.98
- Source
- Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 /…
- Molecule
- Uncharacterized protein Lpg0189
- UniProt
- Q5ZZ22
- Pockets
- 5 · best druggability 0.67
Structure
x-ray diffraction · resolution 1.98 · 1 distinct chain · 28% helix, 36% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Uncharacterized protein Lpg0189 | protein | 264 | 28% helix, 36% strand | Q5ZZ22 |
Ligands and binding sites
- GOL · Glycerol · additive · chains B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 481 | 0.67 | 0.79 | 50 | empty |
| 2 | 266 | 0.65 | 0.82 | 34 | empty |
| 3 | 51 | 0.61 | 0.93 | 22 | empty |
| 4 | 187 | 0.43 | 0.73 | 33 | empty |
| 5 | 74 | 0.41 | 0.80 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 1364 Ų buried · 22 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 14 modified, 2 disulfide (engineered, disulfide).
Compared structures
- 6L6G · Crystal structure of SEMET_LPG0189 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5ZZ22
- Elsewhere: RCSB PDB 6L6G · PDBe 6L6G · UniProt Q5ZZ22
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