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Crystal structure of Ankyrin B/NdeL1 complex

Analyse Crystal structure of Ankyrin B/NdeL1 complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6KZJ
Type: protein
Length: 150 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.5
Source: Homo sapiens; Mus musculus
Molecule: Ankyrin-2; Nuclear distribution protein nudE-like 1
UniProt: Q01484, Q9ERR1
Pockets: 1 · best druggability 0.35

Structure

x-ray diffraction · resolution 1.5 · 3 distinct chains · 75% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ankyrin-2	protein	69	75% helix, 0% strand	Q01484
B	Nuclear distribution protein nudE-like 1	protein	39	69% helix, 3% strand	Q9ERR1
C	Nuclear distribution protein nudE-like 1	protein	42	79% helix, 2% strand	Q9ERR1

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	60	0.35	0.78	13	empty

Interfaces

3 interfaces between chains.

A–B · 1448 Å² buried · 8 hydrogen bonds · protein-protein
A–C · 1124 Å² buried · 10 hydrogen bonds · protein-protein
B–C · 531 Å² buried · 5 hydrogen bonds · protein-protein

Compared structures

6KZJ · Crystal structure of ankyrin B/NDEL1 complex · the same entry in another collection · chain A against A, TM-score 1.00
Q9ERR1 · AlphaFold monomer V2.0 prediction for nuclear distribution protein nude-like 1 (Q9ERR1) · a predicted model of the same protein · chain C against A, TM-score 0.70

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q01484
Every structure of UniProt Q9ERR1
Elsewhere: RCSB PDB 6KZJ · PDBe 6KZJ · UniProt Q01484 · UniProt Q9ERR1

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