Research workbench

RLGS-yUbr1 Ubr box

Analyse RLGS-yUbr1 Ubr box in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6KGI
Type: protein
Length: 86 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.04
Source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Molecule: E3 ubiquitin-protein ligase UBR1
EC: 2.3.2.27
UniProt: P19812
Ligands: ZN
Pockets: 1 · best druggability 0.32

Structure

x-ray diffraction · resolution 1.04 · 1 distinct chain · 10% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
B	E3 ubiquitin-protein ligase UBR1 (EC 2.3.2.27)	protein	86	10% helix, 19% strand	P19812

Ligands and binding sites

ZN · Zinc ion · metal · 3 copies · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	67	0.32	0.76	18	empty

Compared structures

6KGI · Rlgs-YUBR1 ubr box · the same entry in another collection · chain B against B, TM-score 1.00
P19812 · AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase UBR1 (P19812) · a predicted model of the same protein · chain B against A, TM-score 0.88

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P19812
Elsewhere: RCSB PDB 6KGI · PDBe 6KGI · UniProt P19812

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