Research workbench
Crystal structure of Actinomycin D- d(TTGGCGAA) complex
Analyse Crystal structure of Actinomycin D- d(TTGGCGAA) complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6J0H
- Type
- protein + DNA
- Length
- 18 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.52
- Molecule
- DNA (5'-D(P*TP*TP*GP*GP*CP*GP*AP*A)-3'); Actinomycin D
- Ligands
- NA
Structure
x-ray diffraction · resolution 1.52 · 2 distinct chains · 0% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | DNA (5'-D(P*TP*TP*GP*GP*CP*GP*AP*A)-3') | dna | 8 | — | — |
| B | Actinomycin D | protein | 10 | 0% helix, 20% strand | — |
Ligands and binding sites
- NA · Sodium ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
1 interface between chains.
- A–B · 236 Ų buried · 2 hydrogen bonds · protein-nucleic
Modifications
Observed in the structure: 4 modified, 2 d-amino (methylation, D-amino acid).
Compared structures
- 6J0H · Crystal structure of actinomycin D- D(TTGGCGAA) complex · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 6J0H · PDBe 6J0H
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.