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Crystal structure of CqsB2 from Streptomyces exfoliatus 2419-SVT2 (apo form)

Analyse Crystal structure of CqsB2 from Streptomyces exfoliatus 2419-SVT2 (apo form) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6IPV
Type: protein
Length: 884 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.2
Source: Streptomyces exfoliatus
Molecule: CqsB2
Pockets: 10 · best druggability 0.81

Structure

x-ray diffraction · resolution 2.2 · 1 distinct chain · 36% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D	CqsB2	protein	221	36% helix, 28% strand	—

Pockets

10 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	122	0.81	0.98	25	empty
2	121	0.81	0.98	25	empty
3	130	0.81	0.97	25	empty
4	117	0.80	0.97	26	empty
5	706	0.73	0.79	80	empty

Interfaces

5 interfaces between chains.

C–D · 4735 Å² buried · 65 hydrogen bonds · protein-protein
A–B · 4654 Å² buried · 66 hydrogen bonds · protein-protein
B–C · 172 Å² buried · 2 hydrogen bonds · protein-protein
B–D · 93 Å² buried · 0 hydrogen bonds · protein-protein
A–D · 18 Å² buried · 0 hydrogen bonds · protein-protein

Compared structures

6IPV · Crystal structure of CQSB2 from streptomyces exfoliatus 2419-SVT2 (apo form) · the same entry in another collection · chain A against A, TM-score 1.00

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Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 6IPV · PDBe 6IPV

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