Research workbench
Crystal structure of the head domain of human CCDC61
Analyse Crystal structure of the head domain of human CCDC61 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6HXT
- Type
- protein
- Length
- 365 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.55
- Source
- Homo sapiens
- Molecule
- Coiled-coil domain-containing protein 61
- UniProt
- Q9Y6R9
- Pockets
- 5 · best druggability 0.71
Structure
x-ray diffraction · resolution 2.55 · 3 distinct chains · 25% helix, 48% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Coiled-coil domain-containing protein 61 | protein | 118 | 25% helix, 49% strand | Q9Y6R9 |
| B | Coiled-coil domain-containing protein 61 | protein | 120 | 26% helix, 49% strand | Q9Y6R9 |
| C | Coiled-coil domain-containing protein 61 | protein | 127 | 24% helix, 46% strand | Q9Y6R9 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 63 | 0.71 | 0.97 | 23 | empty |
| 2 | 50 | 0.36 | 0.80 | 13 | empty |
| 3 | 76 | 0.33 | 0.75 | 20 | empty |
| 4 | 63 | 0.32 | 0.75 | 15 | empty |
| 5 | 67 | 0.27 | 0.72 | 17 | empty |
Interfaces
3 interfaces between chains.
- A–B · 907 Ų buried · 9 hydrogen bonds · protein-protein
- B–C · 599 Ų buried · 20 hydrogen bonds · protein-protein
- A–C · 478 Ų buried · 6 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 9 modified (engineered).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9Y6R9
- Elsewhere: RCSB PDB 6HXT · PDBe 6HXT · UniProt Q9Y6R9
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