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Structure of ARF1 RNA

Analyse Structure of ARF1 RNA in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
6HU6
Type
RNA
Length
57 nucleotides
Chains
4
Method
x-ray diffraction
Collection
MolNFT v2 / PDB Bank
Contract
0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner
0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution
1.904
Molecule
RNA (19-mer); RNA (5'-R(*GP*AP*GP*UP*GP*CP*CP*AP*GP*A)-3'); RNA…
Ligands
NH4
Pockets
1 · best druggability 0.48

Structure

x-ray diffraction · resolution 1.904 · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
ARNA (19-mer)rna19——
ERNA (19-mer)rna19——
BRNA (5'-R(*GP*AP*GP*UP*GP*CP*CP*AP*GP*A)-3')rna10——
FRNA (5'-R(*CP*UP*GP*GP*UP*AP*CP*UP*C)-3')rna9——

Ligands and binding sites

  • NH4 · Ammonium ion · ion · 3 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13470.480.7227empty

Interfaces

5 interfaces between chains.

  • A–E · 908 Ų buried · 109 hydrogen bonds · nucleic-nucleic
  • B–F · 459 Ų buried · 54 hydrogen bonds · nucleic-nucleic
  • E–F · 92 Ų buried · 2 hydrogen bonds · nucleic-nucleic
  • A–B · 88 Ų buried · 2 hydrogen bonds · nucleic-nucleic
  • E–B · 83 Ų buried · 2 hydrogen bonds · nucleic-nucleic

Compared structures

  • 6HU6 · Structure of ARF1 RNA · the same entry in another collection · chain A against A, TM-score 1.00

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