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Selenomethionine derivative of IdmH 96-104 loop truncation variant

Analyse Selenomethionine derivative of IdmH 96-104 loop truncation variant in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6HNL
Type: protein
Length: 257 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.2
Source: Streptomyces antibioticus
Molecule: Putative polyketide cyclase IdmH
UniProt: C5HV10
Pockets: 4 · best druggability 0.74

Structure

x-ray diffraction · resolution 2.2 · 2 distinct chains · 36% helix, 42% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative polyketide cyclase IdmH	protein	128	36% helix, 42% strand	C5HV10
B	Putative polyketide cyclase IdmH	protein	129	36% helix, 42% strand	C5HV10

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	263	0.74	0.87	29	empty
2	323	0.74	0.86	30	empty
3	76	0.44	0.81	20	empty
4	72	0.40	0.79	21	empty

Interfaces

1 interface between chains.

A–B · 1136 Å² buried · 10 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 10 modified (engineered).

Compared structures

6HNL · Selenomethionine derivative of idmh 96-104 loop truncation variant · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt C5HV10
Elsewhere: RCSB PDB 6HNL · PDBe 6HNL · UniProt C5HV10

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