Research workbench
Coiled-coil domain-containing protein 90B residues 43-125 from Homo sapiens fused to a GCN4 adaptor
Analyse Coiled-coil domain-containing protein 90B residues 43-125 from Homo sapiens… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6H9M
- Type
- protein
- Length
- 282 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.1
- Source
- Homo sapiens; Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
- Molecule
- Coiled-coil domain-containing protein 90B, mitochondrial,General control protein GCN4
- UniProt
- Q9GZT6, P03069
- Pockets
- 1 · best druggability 0.73
Structure
x-ray diffraction · resolution 2.1 · 1 distinct chain · 88% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Coiled-coil domain-containing protein 90B, mitochondrial,General control protein GCN4 | protein | 94 | 88% helix, 2% strand | Q9GZT6, P03069 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 114 | 0.73 | 0.93 | 19 | empty |
Interfaces
3 interfaces between chains.
- B–C · 1799 Ų buried · 14 hydrogen bonds · protein-protein
- A–B · 1774 Ų buried · 9 hydrogen bonds · protein-protein
- A–C · 1713 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
- 6H9M · Coiled-coil domain-containing protein 90B residues 43-125 from homo sapiens fused to a… · the same entry in another collection · chain A against A, TM-score 1.00
- Q9GZT6 · AlphaFold monomer V2.0 prediction for coiled-coil domain-containing protein 90B… · a predicted model of the same protein · chain B against A, TM-score 0.72
- P03069 · AlphaFold monomer V2.0 prediction for general control transcription factor GCN4 (P03069) · a predicted model of the same protein · chain A against A, TM-score 0.50
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9GZT6
- Every structure of UniProt P03069
- Elsewhere: RCSB PDB 6H9M · PDBe 6H9M · UniProt Q9GZT6 · UniProt P03069
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