Research workbench
Structure of human Heat shock protein 90-alpha N-terminal domain (Hsp90-NTD) variant K112R
Analyse Structure of human Heat shock protein 90-alpha N-terminal domain (Hsp90-NTD)… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6GR4
- Type
- protein
- Length
- 209 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.5
- Source
- Homo sapiens
- Molecule
- Heat shock protein HSP 90-alpha
- UniProt
- P07900
- Ligands
- MG, CL
- Pockets
- 1 · best druggability 0.60
Structure
x-ray diffraction · resolution 1.5 · 1 distinct chain · 44% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Heat shock protein HSP 90-alpha | protein | 209 | 44% helix, 22% strand | P07900 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 174 | 0.60 | 0.83 | 26 | empty |
Compared structures
- 6GR4 · Structure of human heat shock protein 90-alpha N-terminal domain (HSP90-ntd) variant K112R · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P07900
- Elsewhere: RCSB PDB 6GR4 · PDBe 6GR4 · UniProt P07900
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