Research workbench
Structure of Lph2 , a novel bidirectional nuclear transport receptor in S. cerevisiae
Analyse Structure of Lph2 , a novel bidirectional nuclear transport receptor in S.… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 6FVB
- Type
- protein
- Length
- 1,001 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 3.297
- Source
- Saccharomyces cerevisiae S288c
- Molecule
- Importin beta-like protein KAP120
- UniProt
- Q02932
- Pockets
- 14 · best druggability 0.62
Structure
x-ray diffraction · resolution 3.297 · 1 distinct chain · 72% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Importin beta-like protein KAP120 | protein | 1001 | 72% helix, 0% strand | Q02932 |
Pockets
14 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 295 | 0.62 | 0.79 | 41 | empty |
| 2 | 111 | 0.61 | 0.86 | 27 | empty |
| 3 | 241 | 0.56 | 0.78 | 23 | empty |
| 4 | 88 | 0.43 | 0.79 | 19 | empty |
| 5 | 94 | 0.43 | 0.78 | 22 | empty |
Modifications
Observed in the structure: 18 modified (engineered).
Compared structures
- 6FVB · Structure of LPH2 , a novel bidirectional nuclear transport receptor in S. cerevisiae · the same entry in another collection · chain A against A, TM-score 1.00
- Q02932 · AlphaFold monomer V2.0 prediction for importin beta-like protein KAP120 (Q02932) · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q02932
- Elsewhere: RCSB PDB 6FVB · PDBe 6FVB · UniProt Q02932
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