Research workbench

S177G Mutant of Yeast PCNA

Analyse S177G Mutant of Yeast PCNA in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6CX2
Type: protein
Length: 254 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 3.101
Source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Molecule: Proliferating cell nuclear antigen
UniProt: P15873
Pockets: 3 · best druggability 0.38

Structure

x-ray diffraction · resolution 3.101 · 1 distinct chain · 20% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Proliferating cell nuclear antigen	protein	254	20% helix, 44% strand	P15873

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	75	0.38	0.78	20	empty
2	52	0.34	0.78	14	empty
3	75	0.32	0.74	18	empty

Compared structures

6CX2 · S177G mutant of yeast PCNA · the same entry in another collection · chain A against A, TM-score 1.00
P15873 · AlphaFold monomer V2.0 prediction for proliferating cell nuclear antigen (P15873) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P15873
Elsewhere: RCSB PDB 6CX2 · PDBe 6CX2 · UniProt P15873

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