Research workbench

Mycobacterium marinum cytochrome P450 CYP268A2 in complex with pseudoio

Analyse Mycobacterium marinum cytochrome P450 CYP268A2 in complex with pseudoio in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6BLD
Type: protein
Length: 414 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.997
Source: Mycobacterium marinum
Molecule: Cytochrome P450 268A2 Cyp268A2
UniProt: B2HMF7
Ligands: HEM, DXJ
Pockets: 3 · best druggability 0.87

Structure

x-ray diffraction · resolution 1.997 · 1 distinct chain · 53% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cytochrome P450 268A2 Cyp268A2	protein	414	53% helix, 10% strand	B2HMF7

Ligands and binding sites

HEM · Protoporphyrin IX containing Fe · ligand · chains A
DXJ · (3E,5E)-6,10-dimethylundeca-3,5,9-trien-2-one · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	397	0.87	0.95	64	HEM, DXJ
2	147	0.57	0.82	25	empty
3	76	0.33	0.75	24	empty

Compared structures

6BLD · Mycobacterium marinum cytochrome P450 CYP268A2 in complex with pseudoionone · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B2HMF7
Elsewhere: RCSB PDB 6BLD · PDBe 6BLD · UniProt B2HMF7

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.