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Crystal Structure of the 16mer GCAGNCUUAAGUCUGC containing BrPh 7-triazolyl-8-aza-7-deazaadenosine

Analyse Crystal Structure of the 16mer GCAGNCUUAAGUCUGC containing BrPh… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 6BGB
Type: RNA
Length: 48 nucleotides
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.65
Molecule: (5'-R(*GP*CP*AP*GP*(A7C)P*CP*UP*UP*AP*AP*GP*UP*CP*UP*GP*C)-3')
Pockets: 1 · best druggability 0.58

Structure

x-ray diffraction · resolution 1.65 · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C	(5'-R(GPCPAPGP(A7C)PCPUPUPAPAPGPUPCPUPGPC)-3')	rna	16	—	—

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	503	0.58	0.74	24	empty

Interfaces

3 interfaces between chains.

A–B · 755 Å² buried · 72 hydrogen bonds · nucleic-nucleic
A–C · 120 Å² buried · 1 hydrogen bond · nucleic-nucleic
B–C · 111 Å² buried · 1 hydrogen bond · nucleic-nucleic

Modifications

Observed in the structure: 3 modified (nucleotide modification).

Compared structures

6BGB · Crystal structure of the 16MER gcagncuuaagucugc containing brph 7… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 6BGB · PDBe 6BGB

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