Research workbench
The closed-conformation crystal structure of the full-length pestivirus NS3 with its NS4A protease cofactor segment
Analyse The closed-conformation crystal structure of the full-length pestivirus NS3… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5WX1
- Type
- protein
- Length
- 693 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.35
- Source
- Classical swine fever virus
- Molecule
- Serine protease NS3
- UniProt
- Q5U8X5
- Pockets
- 7 · best druggability 0.64
Structure
x-ray diffraction · resolution 2.35 · 1 distinct chain · 26% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Serine protease NS3 | protein | 693 | 26% helix, 30% strand | Q5U8X5 |
Pockets
7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 254 | 0.64 | 0.82 | 38 | empty |
| 2 | 592 | 0.62 | 0.74 | 63 | empty |
| 3 | 118 | 0.59 | 0.86 | 25 | empty |
| 4 | 230 | 0.54 | 0.77 | 35 | empty |
| 5 | 104 | 0.45 | 0.78 | 15 | empty |
Compared structures
- 5WX1 · The closed-conformation crystal structure of the full-length pestivirus NS3 with its NS4A… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5U8X5
- Elsewhere: RCSB PDB 5WX1 · PDBe 5WX1 · UniProt Q5U8X5
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.