Research workbench
Crystal structure of Plasmodium vivax AMA1 in complex with a 39 aa PvRON2 peptide
Analyse Crystal structure of Plasmodium vivax AMA1 in complex with a 39 aa PvRON2… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5NQG
- Type
- protein
- Length
- 415 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.15
- Source
- PLASMODIUM VIVAX SAL-1; SYNTHETIC CONSTRUCT
- Molecule
- Apical merozoite antigen 1; RON2
- UniProt
- O61130, A5K3N8
- Pockets
- 4 · best druggability 0.48
Structure
x-ray diffraction · resolution 2.15 · 2 distinct chains · 19% helix, 28% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Apical merozoite antigen 1 | protein | 382 | 19% helix, 28% strand | O61130 |
| B | RON2 | protein | 33 | 18% helix, 27% strand | A5K3N8 |
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 125 | 0.48 | 0.79 | 26 | empty |
| 2 | 95 | 0.40 | 0.76 | 23 | empty |
| 3 | 91 | 0.38 | 0.76 | 18 | empty |
| 4 | 87 | 0.32 | 0.73 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 1451 Ų buried · 17 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 9 disulfide (disulfide).
Compared structures
- 5NQG · Crystal structure of plasmodium vivax AMA1 in complex with a 39 aa PVRON2 peptide · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O61130
- Every structure of UniProt A5K3N8
- Elsewhere: RCSB PDB 5NQG · PDBe 5NQG · UniProt O61130 · UniProt A5K3N8
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.