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Crystal structure of a Se-Met substituted Dictyostelium discoideum ADP-ribose binding macrodomain (residues 342-563) of DDB_G0293866

Analyse Crystal structure of a Se-Met substituted Dictyostelium discoideum ADP-ribose… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 5LW6
Type: protein
Length: 221 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.8
Source: Dictyostelium discoideum
Molecule: DDB_G0293866
UniProt: Q54B72
Pockets: 2 · best druggability 0.73

Structure

x-ray diffraction · resolution 1.8 · 1 distinct chain · 34% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DDB_G0293866	protein	221	34% helix, 16% strand	Q54B72

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	126	0.73	0.93	32	empty
2	52	0.24	0.72	11	empty

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

5LW6 · Crystal structure of a se-met substituted dictyostelium discoideum ADP-ribose binding… · the same entry in another collection · chain A against A, TM-score 1.00

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Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q54B72
Elsewhere: RCSB PDB 5LW6 · PDBe 5LW6 · UniProt Q54B72

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