Research workbench
The crystal structure of a functionally uncharacterized protein LPG0634 from Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Analyse The crystal structure of a functionally uncharacterized protein LPG0634 from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5ES2
- Type
- protein
- Length
- 777 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.6
- Source
- Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 /…
- Molecule
- Uncharacterized protein LPG0634
- UniProt
- Q5ZXU7
- Ligands
- SO4
- Pockets
- 8 · best druggability 0.66
Structure
x-ray diffraction · resolution 2.6 · 2 distinct chains · 64% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized protein LPG0634 | protein | 388 | 65% helix, 2% strand | Q5ZXU7 |
| B | Uncharacterized protein LPG0634 | protein | 389 | 63% helix, 2% strand | Q5ZXU7 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 14 copies · chains A, B
- ACT · Acetate ion · additive · 6 copies · chains A, B
- EDO · 1,2-ethanediol · additive · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 596 | 0.66 | 0.76 | 64 | ACT, SO4 |
| 2 | 548 | 0.65 | 0.76 | 56 | ACT |
| 3 | 138 | 0.41 | 0.74 | 19 | empty |
| 4 | 131 | 0.40 | 0.74 | 19 | empty |
| 5 | 106 | 0.40 | 0.76 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 100 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 24 modified (engineered).
Compared structures
- 5ES2 · The crystal structure of a functionally uncharacterized protein LPG0634 from legionella… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5ZXU7
- Elsewhere: RCSB PDB 5ES2 · PDBe 5ES2 · UniProt Q5ZXU7
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.