Research workbench
Structure of Dictyostelium Discoideum Myosin VII MyTH4-FERM MF2 domain
Analyse Structure of Dictyostelium Discoideum Myosin VII MyTH4-FERM MF2 domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 5EJR
- Type
- protein
- Length
- 503 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2
- Source
- Dictyostelium discoideum
- Molecule
- Myosin-I heavy chain
- UniProt
- Q9U1M8
- Pockets
- 6 · best druggability 0.72
Structure
x-ray diffraction · resolution 2 · 1 distinct chain · 50% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Myosin-I heavy chain | protein | 503 | 50% helix, 14% strand | Q9U1M8 |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · 7 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 627 | 0.72 | 0.79 | 57 | EDO |
| 2 | 182 | 0.47 | 0.75 | 24 | empty |
| 3 | 96 | 0.45 | 0.79 | 16 | empty |
| 4 | 86 | 0.40 | 0.78 | 20 | EDO |
| 5 | 50 | 0.30 | 0.77 | 13 | EDO |
Compared structures
- 5EJR · Structure of dictyostelium discoideum myosin VII MYTH4-ferm MF2 domain · the same entry in another collection · chain A against A, TM-score 1.00
- Q9U1M8 · AlphaFold monomer V2.0 prediction for myosin-I heavy chain (Q9U1M8) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9U1M8
- Elsewhere: RCSB PDB 5EJR · PDBe 5EJR · UniProt Q9U1M8
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