Research workbench
Crystal structure of anti-IL4 darpin 44C12V5
Analyse Crystal structure of anti-IL4 darpin 44C12V5 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4YDW
- Type
- protein
- Length
- 313 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.9
- Source
- synthetic construct
- Molecule
- Darpin 44C12V5
- Pockets
- 2 · best druggability 0.71
Structure
x-ray diffraction · resolution 1.9 · 2 distinct chains · 53% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Darpin 44C12V5 | protein | 157 | 53% helix, 0% strand | — |
| B | Darpin 44C12V5 | protein | 156 | 54% helix, 0% strand | — |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 942 | 0.71 | 0.75 | 60 | empty |
| 2 | 93 | 0.41 | 0.78 | 21 | empty |
Interfaces
1 interface between chains.
- A–B · 568 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 4YDW · Crystal structure of anti-IL4 darpin 44C12V5 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 4YDW · PDBe 4YDW
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.