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The crystal structure of a functionally-unknown protein from Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Analyse The crystal structure of a functionally-unknown protein from Legionella… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 4RD8
- Type
- protein
- Length
- 428 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.72
- Source
- Legionella pneumophila subsp. pneumophila str. Philadelphia 1
- Molecule
- Uncharacterized protein
- UniProt
- Q5ZU48
- Pockets
- 5 · best druggability 0.51
Structure
x-ray diffraction · resolution 1.72 · 2 distinct chains · 63% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized protein | protein | 210 | 64% helix, 2% strand | Q5ZU48 |
| B | Uncharacterized protein | protein | 218 | 61% helix, 2% strand | Q5ZU48 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 65 | 0.51 | 0.86 | 19 | empty |
| 2 | 69 | 0.46 | 0.83 | 16 | empty |
| 3 | 88 | 0.40 | 0.77 | 17 | empty |
| 4 | 71 | 0.39 | 0.78 | 17 | empty |
| 5 | 63 | 0.38 | 0.79 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 854 Ų buried · 7 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 11 modified (engineered).
Compared structures
- 4RD8 · The crystal structure of a functionally-unknown protein from legionella pneumophila… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5ZU48
- Elsewhere: RCSB PDB 4RD8 · PDBe 4RD8 · UniProt Q5ZU48
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