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Crystal Structure Of glutathione transferase YghU from Streptococcus pneumoniae ATCC 700669, complexed with glutathione, Target EFI-507284

Analyse Crystal Structure Of glutathione transferase YghU from Streptococcus pneumoniae… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4PUA
Type: protein
Length: 261 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.708
Source: Streptococcus pneumoniae
Molecule: glutathione S-transferase
EC: 2.5.1.18
UniProt: B8ZLL4
Ligands: GSH
Pockets: 1 · best druggability 0.64

Structure

x-ray diffraction · resolution 1.708 · 1 distinct chain · 51% helix, 10% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	glutathione S-transferase (EC 2.5.1.18)	protein	261	51% helix, 10% strand	B8ZLL4

Ligands and binding sites

GSH · Glutathione · ligand · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	508	0.64	0.77	48	GSH

Compared structures

4PUA · Crystal structure of glutathione transferase yghu from streptococcus pneumoniae atcc… · the same entry in another collection · chain A against A, TM-score 1.00

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Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt B8ZLL4
Elsewhere: RCSB PDB 4PUA · PDBe 4PUA · UniProt B8ZLL4

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