Research workbench

Crystal structure of T. acidophilum IdeR

Analyse Crystal structure of T. acidophilum IdeR in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4O5V
Type: protein
Length: 213 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.1
Source: Thermoplasma acidophilum
Molecule: Iron-dependent transcription repressor related protein
UniProt: Q9HJU1
Ligands: FE2
Pockets: 2 · best druggability 0.56

Structure

x-ray diffraction · resolution 2.1 · 1 distinct chain · 46% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Iron-dependent transcription repressor related protein	protein	213	46% helix, 21% strand	Q9HJU1

Ligands and binding sites

FE2 · Fe (II) ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	172	0.56	0.81	20	empty
2	104	0.42	0.77	19	empty

Modifications

Observed in the structure: 5 modified (engineered).

Compared structures

4O5V · Crystal structure of T. acidophilum ider · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9HJU1
Elsewhere: RCSB PDB 4O5V · PDBe 4O5V · UniProt Q9HJU1

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.