Research workbench
AlphaFold monomer V2.0 prediction for alpha-2C adrenergic receptor (P35405)
Analyse AlphaFold monomer V2.0 prediction for alpha-2C adrenergic receptor (P35405) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P35405
- Type
- protein
- Length
- 469 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x46EfCa788d03A3e879DAcDb96552AB8Bbc7e20b3
- Molecule
- Alpha-2C adrenergic receptor
- UniProt
- P35405
- Pockets
- 7 · best druggability 0.71
Structure
1 distinct chain · 67% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Alpha-2C adrenergic receptor | protein | 469 | 67% helix, 0% strand | P35405 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 290 | 0.71 | 0.85 | 28 | empty |
| 2 | 266 | 0.66 | 0.82 | 40 | empty |
| 3 | 477 | 0.64 | 0.77 | 38 | empty |
| 4 | 62 | 0.39 | 0.79 | 13 | empty |
| 5 | 66 | 0.31 | 0.74 | 14 | empty |
Modifications
Observed in the structure: 2 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P35405
- Elsewhere: UniProt P35405 · AlphaFold DB P35405
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