Research workbench
AlphaFold monomer V2.0 prediction for alpha-1A adrenergic receptor (P18130)
Analyse AlphaFold monomer V2.0 prediction for alpha-1A adrenergic receptor (P18130) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P18130
- Type
- protein
- Length
- 466 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x13D0a95FDcd918ebb5150FD2C57cfC72eC29DA05
- Molecule
- Alpha-1A adrenergic receptor
- UniProt
- P18130
- Pockets
- 5 · best druggability 0.71
Structure
1 distinct chain · 57% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Alpha-1A adrenergic receptor | protein | 466 | 57% helix, 6% strand | P18130 |
Pockets
5 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 55 | 0.71 | 0.98 | 20 | empty |
| 2 | 585 | 0.70 | 0.79 | 53 | empty |
| 3 | 161 | 0.61 | 0.84 | 24 | empty |
| 4 | 200 | 0.56 | 0.79 | 29 | empty |
| 5 | 51 | 0.28 | 0.75 | 14 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P18130
- Elsewhere: UniProt P18130 · AlphaFold DB P18130
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