AlphaFold monomer V2.0 prediction for chymosin (P00794)

Structure

1 distinct chain · 20% helix, 40% strand (DSSP).

Pockets

4 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

• 1CMS · The three-dimensional structure of recombinant bovine chymosin at 2.3 ångströms resolution · an experimental structure of the same protein · chain A against A, TM-score 0.83
• 1CMS · The three-dimensional structure of recombinant bovine chymosin at 2.3 ångströms resolution · an experimental structure of the same protein · chain A against A, TM-score 0.83
• 4AA8 · Bovine chymosin at 1.8A resolution · an experimental structure of the same protein · chain A against A, TM-score 0.83
• 4AA8 · Bovine chymosin at 1.8A resolution · an experimental structure of the same protein · chain A against A, TM-score 0.83
• 4AUC · Bovine chymosin in complex with pepstatin a · an experimental structure of the same protein · chain A against A, TM-score 0.83
• 4AUC · Bovine chymosin in complex with Pepstatin A · an experimental structure of the same protein · chain A against A, TM-score 0.83
• 3CMS · Engineering enzyme sub-site specificity: preparation, kinetic characterization and X-ray… · an experimental structure of the same protein · chain A against A, TM-score 0.82
• 3CMS · Engineering enzyme sub-site specificity: preparation, kinetic characterization and X-ray… · an experimental structure of the same protein · chain A against A, TM-score 0.82
• 4CMS · X-ray analyses of aspartic proteinases IV. structure and refinement at 2.2 ångströms… · an experimental structure of the same protein · chain A against A, TM-score 0.82
• 4CMS · X-ray analyses of aspartic proteinases IV. structure and refinement at 2.2 ångströms… · an experimental structure of the same protein · chain A against A, TM-score 0.82
• 1CZI · Chymosin complex with the inhibitor cp-113972 · an experimental structure of the same protein · chain A against E, TM-score 0.82
• 1CZI · Chymosin complex with the inhibitor cp-113972 · an experimental structure of the same protein · chain A against E, TM-score 0.82

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt P00794
• Elsewhere: UniProt P00794 · AlphaFold DB P00794