Research workbench
AlphaFold monomer V2.0 prediction for aspartic proteinase yapsin-1 (O59774)
Analyse AlphaFold monomer V2.0 prediction for aspartic proteinase yapsin-1 (O59774) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O59774
- Type
- protein
- Length
- 521 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xBeB220F0B5b0C48F46B5DDd3E3b071BC0827f8D6
- Molecule
- Aspartic proteinase yapsin-1
- UniProt
- O59774
- Pockets
- 7 · best druggability 0.72
Structure
1 distinct chain · 9% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Aspartic proteinase yapsin-1 | protein | 521 | 9% helix, 38% strand | O59774 |
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 806 | 0.72 | 0.77 | 63 | empty |
| 2 | 323 | 0.63 | 0.79 | 38 | empty |
| 3 | 50 | 0.40 | 0.82 | 15 | empty |
| 4 | 112 | 0.38 | 0.75 | 20 | empty |
| 5 | 74 | 0.37 | 0.77 | 14 | empty |
Modifications
Observed in the structure: 3 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O59774
- Elsewhere: UniProt O59774 · AlphaFold DB O59774
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