Research workbench
AlphaFold monomer V2.0 prediction for NAD(P)H-dependent D-xylose reductase (O74237)
Analyse AlphaFold monomer V2.0 prediction for NAD(P)H-dependent D-xylose reductase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- O74237
- Type
- protein
- Length
- 322 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xc0F878C3f3E2a1874e2A6daC80d429e553DdB0D5
- Molecule
- NAD(P)H-dependent D-xylose reductase
- UniProt
- O74237
- Pockets
- 2 · best druggability 0.72
Structure
1 distinct chain · 39% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | NAD(P)H-dependent D-xylose reductase | protein | 322 | 39% helix, 15% strand | O74237 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 315 | 0.72 | 0.85 | 42 | empty |
| 2 | 63 | 0.31 | 0.75 | 19 | empty |
Compared structures
- 1K8C · Crystal structure of dimeric xylose reductase in complex with NADP(H) · an experimental structure of the same protein · chain A against B, TM-score 0.99
- 1K8C · Crystal structure of dimeric xylose reductase in complex with NADP(H) · an experimental structure of the same protein · chain A against B, TM-score 0.99
- 1MI3 · 1.8 ångström structure of xylose reductase from candida tenuis in complex with NAD · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1MI3 · 1.8 Angstrom structure of xylose reductase from Candida tenuis in complex with NAD · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1Z9A · Crystal Structure Of The Asn-309 To Asp Mutant Of Candida Tenuis Xylose Reductase… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1Z9A · Crystal structure of the asn-309 to asp mutant of candida tenuis xylose reductase… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1YE4 · Crystal structure of the Lys-274 to Arg mutant of Candida tenuis xylose reductase… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1YE4 · Crystal structure of the lys-274 to arg mutant of candida tenuis xylose reductase… · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1R38 · Crystal structure of H114A mutant of candida tenuis xylose reductase · an experimental structure of the same protein · chain A against A, TM-score 0.99
- 1R38 · Crystal structure of H114A mutant of Candida tenuis xylose reductase · an experimental structure of the same protein · chain A against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O74237
- Elsewhere: UniProt O74237 · AlphaFold DB O74237
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