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AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase WNK4 (Q80UE6)

Analyse AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase WNK4… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q80UE6
Type
protein
Length
1,222 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x7Fe8EC3e2F52E83fc61c087D6Dd75E8584fB57B4
Molecule
SERINE/THREONINE-protein kinase WNK4
UniProt
Q80UE6
Pockets
6 · best druggability 0.69

Structure

1 distinct chain · 19% helix, 9% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ASERINE/THREONINE-protein kinase WNK4protein122219% helix, 9% strandQ80UE6

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13160.690.8344empty
22440.540.7732empty
31700.440.7523empty
4750.400.7914empty
5530.310.7713empty

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