Research workbench
AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase WNK1 (Q9CAV6)
Analyse AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase WNK1… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q9CAV6
- Type
- protein
- Length
- 700 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x074B355E6B4396890e7f52FF4c3a7ab517E7705a
- Molecule
- SERINE/THREONINE-protein kinase WNK1
- UniProt
- Q9CAV6
- Pockets
- 7 · best druggability 0.81
Structure
1 distinct chain · 29% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | SERINE/THREONINE-protein kinase WNK1 | protein | 700 | 29% helix, 13% strand | Q9CAV6 |
Pockets
7 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 964 | 0.81 | 0.83 | 91 | empty |
| 2 | 335 | 0.66 | 0.80 | 44 | empty |
| 3 | 250 | 0.55 | 0.77 | 38 | empty |
| 4 | 65 | 0.43 | 0.81 | 18 | empty |
| 5 | 54 | 0.35 | 0.78 | 14 | empty |
Modifications
Observed in the structure: 1 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9CAV6
- Elsewhere: UniProt Q9CAV6 · AlphaFold DB Q9CAV6
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