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AlphaFold monomer V2.0 prediction for whirlin (Q80VW5)

Analyse AlphaFold monomer V2.0 prediction for whirlin (Q80VW5) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q80VW5
Type
protein
Length
918 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x3F7c838ccc23133e72aA1c8841D2c157C4B4810a
Molecule
Whirlin
UniProt
Q80VW5
Pockets
9 · best druggability 0.65

Structure

1 distinct chain · 22% helix, 15% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AWhirlinprotein91822% helix, 15% strandQ80VW5

Pockets

9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
13770.650.7828empty
23720.630.7842empty
32000.480.7525empty
4530.440.8413empty
5780.410.7919empty

Compared structures

  • 6Y9O · Crystal structure of whirlin PDZ3_C-ter in complex with cask internal PDZ binding motif… · an experimental structure of the same protein · chain A against A, TM-score 0.10
  • 6Y9O · Crystal structure of Whirlin PDZ3_C-ter in complex with CASK internal PDZ binding motif… · an experimental structure of the same protein · chain A against A, TM-score 0.10
  • 6Y9N · Crystal structure of whirlin PDZ3_C-ter in complex with myosin 15A C- terminal PDZ… · an experimental structure of the same protein · chain A against A, TM-score 0.10
  • 6Y9N · Crystal structure of Whirlin PDZ3_C-ter in complex with Myosin 15a C-terminal PDZ binding… · an experimental structure of the same protein · chain A against A, TM-score 0.10
  • 6Y9P · Crystal structure of Whirlin PDZ3_C-ter in complex with Harmonin a1 C-terminal PDZ… · an experimental structure of the same protein · chain A against A, TM-score 0.10
  • 6Y9P · Crystal structure of whirlin PDZ3_C-ter in complex with harmonin A1 C- terminal PDZ… · an experimental structure of the same protein · chain A against A, TM-score 0.10
  • 6Y9Q · Crystal structure of Whirlin PDZ3_C-ter in complex with Taperin internal PDZ binding… · an experimental structure of the same protein · chain A against B, TM-score 0.10
  • 6Y9Q · Crystal structure of whirlin PDZ3_C-ter in complex with taperin internal PDZ binding… · an experimental structure of the same protein · chain A against B, TM-score 0.10
  • 6Y38 · Crystal structure of whirlin PDZ3 in complex with myosin 15A C- terminal PDZ binding… · an experimental structure of the same protein · chain A against B, TM-score 0.10
  • 6Y38 · Crystal structure of Whirlin PDZ3 in complex with Myosin 15a C-terminal PDZ binding motif… · an experimental structure of the same protein · chain A against B, TM-score 0.10

Analyse

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