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AlphaFold monomer V2.0 prediction for wings apart-like protein homolog (Q7Z5K2)

Analyse AlphaFold monomer V2.0 prediction for wings apart-like protein homolog (Q7Z5K2) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q7Z5K2
Type
protein
Length
1,190 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x20b6eE119323203650E7eF1c5794b5921737553F
Molecule
Wings apart-like protein homolog
UniProt
Q7Z5K2
Pockets
6 · best druggability 0.71

Structure

1 distinct chain · 34% helix, 4% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AWings apart-like protein homologprotein119034% helix, 4% strandQ7Z5K2

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
17880.710.7776empty
22200.530.7729empty
3980.420.7821empty
4530.320.7610empty
5600.280.7415empty

Compared structures

  • 4K6J · Human cohesin inhibitor WapL · an experimental structure of the same protein · chain A against A, TM-score 0.40
  • 4K6J · Human cohesin inhibitor wapl · an experimental structure of the same protein · chain A against A, TM-score 0.40
  • 5HDT · Human cohesin regulator PDS5B bound to a wapl peptide · an experimental structure of the same protein · chain A against E, TM-score 0.00
  • 5HDT · Human cohesin regulator Pds5B bound to a Wapl peptide · an experimental structure of the same protein · chain A against E, TM-score 0.00

Analyse

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