Research workbench
AlphaFold monomer V2.0 prediction for vascular endothelial growth factor receptor 2 (P52583)
Analyse AlphaFold monomer V2.0 prediction for vascular endothelial growth factor… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- P52583
- Type
- protein
- Length
- 1,348 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xA32Fdfbad4dfbdC07f57d6Aa6C5862EDA88D0Ec3
- Molecule
- Vascular endothelial growth factor receptor 2
- UniProt
- P52583
- Pockets
- 10 · best druggability 0.72
Structure
1 distinct chain · 15% helix, 33% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Vascular endothelial growth factor receptor 2 | protein | 1348 | 15% helix, 33% strand | P52583 |
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 454 | 0.72 | 0.82 | 46 | empty |
| 2 | 634 | 0.66 | 0.76 | 67 | empty |
| 3 | 455 | 0.66 | 0.78 | 52 | empty |
| 4 | 287 | 0.54 | 0.75 | 24 | empty |
| 5 | 218 | 0.52 | 0.77 | 24 | empty |
Modifications
Observed in the structure: 10 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P52583
- Elsewhere: UniProt P52583 · AlphaFold DB P52583
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