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AlphaFold monomer V2.0 prediction for vitamin D3 receptor (P13053)

Analyse AlphaFold monomer V2.0 prediction for vitamin D3 receptor (P13053) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P13053
Type
protein
Length
423 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x79a905d858Ce72991FD6E7a9C6498620f42E146D
Molecule
Vitamin D3 receptor
UniProt
P13053
Pockets
4 · best druggability 0.86

Structure

1 distinct chain · 49% helix, 4% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AVitamin D3 receptorprotein42349% helix, 4% strandP13053

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12940.860.9636empty
21880.550.7922empty
3510.300.7610empty
4570.240.7216empty

Compared structures

  • 5GIE · Crystal structure of VDR in complex with DLAM-4P (P21 form) · an experimental structure of the same protein · chain A against A, TM-score 0.56
  • 3VT3 · Crystal structures of rat VDR-LBD with R270L mutation · an experimental structure of the same protein · chain A against A, TM-score 0.56
  • 3VT3 · Crystal structures of rat vdr-lbd with R270L mutation · an experimental structure of the same protein · chain A against A, TM-score 0.56
  • 1RKG · Crystal structure of the rat vitamin D receptor ligand binding domain complexed with… · an experimental structure of the same protein · chain A against A, TM-score 0.56
  • 1RKG · crystal structure of the rat vitamin D receptor ligand binding domain complexed with… · an experimental structure of the same protein · chain A against A, TM-score 0.56
  • 3W0I · Crystal structure of rat vdr ligand binding domain in complex with novel nonsecosteroidal… · an experimental structure of the same protein · chain A against A, TM-score 0.56
  • 3W0I · Crystal Structure of Rat VDR Ligand Binding Domain in Complex with Novel Nonsecosteroidal… · an experimental structure of the same protein · chain A against A, TM-score 0.56
  • 3W0G · Crystal structure of rat vdr ligand binding domain in complex with novel nonsecosteroidal… · an experimental structure of the same protein · chain A against A, TM-score 0.56
  • 3W0G · Crystal Structure of Rat VDR Ligand Binding Domain in Complex with Novel Nonsecosteroidal… · an experimental structure of the same protein · chain A against A, TM-score 0.56
  • 3W0J · Crystal structure of rat vdr ligand binding domain in complex with novel nonsecosteroidal… · an experimental structure of the same protein · chain A against A, TM-score 0.56
  • 3W0J · Crystal Structure of Rat VDR Ligand Binding Domain in Complex with Novel Nonsecosteroidal… · an experimental structure of the same protein · chain A against A, TM-score 0.56
  • 2ZMI · Crystal structure of rat vitamin D receptor bound to adamantyl vitamin D analogs… · an experimental structure of the same protein · chain A against A, TM-score 0.56

Analyse

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