Research workbench
AlphaFold monomer V2.0 prediction for 2-epi-5-epi-valiolone synthase (H2K887)
Analyse AlphaFold monomer V2.0 prediction for 2-epi-5-epi-valiolone synthase (H2K887) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- H2K887
- Type
- protein
- Length
- 414 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0xa73BAb1DabE4333A884D03393eAa10c3B4215494
- Molecule
- 2-epi-5-epi-valiolone synthase
- UniProt
- H2K887
- Pockets
- 2 · best druggability 0.79
Structure
1 distinct chain · 48% helix, 18% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 2-epi-5-epi-valiolone synthase | protein | 414 | 48% helix, 18% strand | H2K887 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 603 | 0.79 | 0.85 | 69 | empty |
| 2 | 86 | 0.31 | 0.73 | 17 | empty |
Compared structures
- 4P53 · ValA (2-epi-5-epi-valiolone synthase) from Streptomyces hygroscopicus subsp.… · an experimental structure of the same protein · chain A against A, TM-score 0.87
- 4P53 · Vala (2-epi-5-epi-valiolone synthase) from streptomyces hygroscopicus subsp.… · an experimental structure of the same protein · chain A against A, TM-score 0.87
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt H2K887
- Elsewhere: UniProt H2K887 · AlphaFold DB H2K887
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