Research workbench
AlphaFold monomer V2.0 prediction for urokinase-type plasminogen activator (Q8MHY7)
Analyse AlphaFold monomer V2.0 prediction for urokinase-type plasminogen activator… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- Accession
- Q8MHY7
- Type
- protein
- Length
- 433 residues
- Chains
- 1
- Collection
- MolNFT v1 / AlphaFold
- Contract
- 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
- Owner
- 0x4Ef77Afb5a3D9F41c95Be3227D1CC986CCb61835
- Molecule
- Urokinase-type plasminogen activator
- UniProt
- Q8MHY7
- Pockets
- 7 · best druggability 0.53
Structure
1 distinct chain · 7% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Urokinase-type plasminogen activator | protein | 433 | 7% helix, 30% strand | Q8MHY7 |
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 105 | 0.53 | 0.83 | 22 | empty |
| 2 | 80 | 0.51 | 0.84 | 21 | empty |
| 3 | 131 | 0.42 | 0.76 | 29 | empty |
| 4 | 131 | 0.39 | 0.74 | 19 | empty |
| 5 | 83 | 0.34 | 0.74 | 19 | empty |
Modifications
Observed in the structure: 12 disulfide (disulfide).
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8MHY7
- Elsewhere: UniProt Q8MHY7 · AlphaFold DB Q8MHY7
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