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AlphaFold monomer V2.0 prediction for S-adenosyl-L-methionine- dependent tRNA 4-demethylwyosine synthase (Q8H8N3)

Analyse AlphaFold monomer V2.0 prediction for S-adenosyl-L-methionine- dependent tRNA… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
Q8H8N3
Type
protein
Length
653 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x97EfFf2d74994e28D3b69b1503Bd9c292B2Df480
Molecule
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase
UniProt
Q8H8N3
Pockets
9 · best druggability 0.86

Structure

1 distinct chain · 39% helix, 15% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AS-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthaseprotein65339% helix, 15% strandQ8H8N3

Pockets

9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
111460.860.8797empty
24690.590.7450empty
3780.400.7812empty
4710.360.7720empty
5830.310.7318empty

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