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AlphaFold monomer V2.0 prediction for hth-type transcriptional regulator tsar (P94678)

Analyse AlphaFold monomer V2.0 prediction for hth-type transcriptional regulator tsar… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P94678
Type
protein
Length
298 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0xf1a8F1556714059A77767ecA75A15ac431c60971
Molecule
Hth-type transcriptional regulator tsar
UniProt
P94678
Pockets
2 · best druggability 0.65

Structure

1 distinct chain · 43% helix, 23% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AHth-type transcriptional regulator tsarprotein29843% helix, 23% strandP94678

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12450.650.8347empty
2850.310.7314empty

Compared structures

  • 3FXU · Crystal structure of tsar in complex with its effector P- toluenesulfonate · an experimental structure of the same protein · chain A against B, TM-score 0.89
  • 3FXU · Crystal structure of TsaR in complex with its effector p-toluenesulfonate · an experimental structure of the same protein · chain A against B, TM-score 0.89
  • 3FZJ · TsaR low resolution crystal structure, tetragonal form · an experimental structure of the same protein · chain A against A, TM-score 0.70
  • 3FZJ · Tsar low resolution crystal structure, tetragonal form · an experimental structure of the same protein · chain A against A, TM-score 0.70
  • 3FXQ · Crystal structure of the LysR-type transcriptional regulator TsaR · an experimental structure of the same protein · chain A against A, TM-score 0.70
  • 3FXQ · Crystal structure of the lysr-type transcriptional regulator tsar · an experimental structure of the same protein · chain A against A, TM-score 0.70
  • 3FXR · Crystal structure of TsaR in complex with sulfate · an experimental structure of the same protein · chain A against A, TM-score 0.70
  • 3FXR · Crystal structure of tsar in complex with sulfate · an experimental structure of the same protein · chain A against A, TM-score 0.70
  • 3N6T · Effector binding domain of tsar · an experimental structure of the same protein · chain A against A, TM-score 0.67
  • 3N6T · Effector binding domain of TsaR · an experimental structure of the same protein · chain A against A, TM-score 0.67

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