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AlphaFold monomer V2.0 prediction for anthranilate phosphoribosyltransferase (P9WFX5)

Analyse AlphaFold monomer V2.0 prediction for anthranilate phosphoribosyltransferase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
P9WFX5
Type
protein
Length
370 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x9188600a0FCa2914254C94299b1bd9721Bc4D500
Molecule
Anthranilate phosphoribosyltransferase
UniProt
P9WFX5
Pockets
1 · best druggability 0.77

Structure

1 distinct chain · 49% helix, 12% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AAnthranilate phosphoribosyltransferaseprotein37049% helix, 12% strandP9WFX5

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
15630.770.8465empty

Compared structures

  • 5C1R · Stereoisomer of prpp bound in the active site of mycobacterium tuberculosis anthranilate… · an experimental structure of the same protein · chain A against B, TM-score 0.93
  • 5C7S · PRPP complexed with two Mn2+ in the active site of Mycobacterium tuberculosis… · an experimental structure of the same protein · chain A against A, TM-score 0.92
  • 5C7S · Prpp complexed with two MN2+ in the active site of mycobacterium tuberculosis… · an experimental structure of the same protein · chain A against A, TM-score 0.92
  • 5C2L · Magnesium soaked into the active site of mycobacterium tuberculosis anthranilate… · an experimental structure of the same protein · chain A against A, TM-score 0.92
  • 5BYT · Prpp complexed with a single mg in the active site of mycobacterium tuberculosis… · an experimental structure of the same protein · chain A against A, TM-score 0.92
  • 5BNE · Bianthranilate-like inhibitor with 6 atom line" and phosphonate "hook" fishing for… · an experimental structure of the same protein · chain A against C, TM-score 0.89
  • 5BNE · Bianthranilate-like inhibitor with 6 atom "line" and phosphonate "hook" fishing for… · an experimental structure of the same protein · chain A against C, TM-score 0.89

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