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AlphaFold monomer V2.0 prediction for methylenetetrahydrofolate-- tRNA-(uracil-5-)-methyltransferase trmfo (A5V4M8)

Analyse AlphaFold monomer V2.0 prediction for methylenetetrahydrofolate… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession
A5V4M8
Type
protein
Length
445 residues
Chains
1
Collection
MolNFT v1 / AlphaFold
Contract
0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner
0x0E5d19AAbEf43d610964131Fe6042A63EE0dd81A
Molecule
Methylenetetrahydrofolate-- tRNA-(uracil-5-)-methyltransferase trmfo
UniProt
A5V4M8
Pockets
5 · best druggability 0.77

Structure

1 distinct chain · 35% helix, 18% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
AMethylenetetrahydrofolate-- tRNA-(uracil-5-)-methyltransferase trmfoprotein44535% helix, 18% strandA5V4M8

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
16990.770.8282empty
2980.500.8216empty
31320.460.7717empty
4980.370.7527empty
5810.320.7423empty

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