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AlphaFold monomer V2.0 prediction for tribbles homolog 2 (Q92519)

Analyse AlphaFold monomer V2.0 prediction for tribbles homolog 2 (Q92519) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: Q92519
Type: protein
Length: 343 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x7782F4817b37743d738e9aF842bf74bd50f2015E
Molecule: Tribbles homolog 2
UniProt: Q92519
Pockets: 3 · best druggability 0.72

Structure

1 distinct chain · 27% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tribbles homolog 2	protein	343	27% helix, 17% strand	Q92519

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	831	0.72	0.77	89	empty
2	103	0.39	0.76	22	empty
3	50	0.36	0.80	17	empty

Compared structures

7UPM · Tribbles (TRIB2) pseudokinase bound to nanobody Nb4.103 · an experimental structure of the same protein · chain A against A, TM-score 0.74

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q92519
Elsewhere: UniProt Q92519 · AlphaFold DB Q92519

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