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AlphaFold monomer V2.0 prediction for tripeptidyl-peptidase 2 (Q9V6K1)

Analyse AlphaFold monomer V2.0 prediction for tripeptidyl-peptidase 2 (Q9V6K1) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

Accession: Q9V6K1
Type: protein
Length: 1,441 residues
Chains: 1
Collection: MolNFT v1 / AlphaFold
Contract: 0xBf7491af3407816DFa88a5EA4c82e8A2B1D721eD
Owner: 0x4925F35C539c838F29Bff8dbDd7f50009BD3f044
Molecule: Tripeptidyl-peptidase 2
UniProt: Q9V6K1
Pockets: 18 · best druggability 0.81

Structure

1 distinct chain · 29% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Tripeptidyl-peptidase 2	protein	1441	29% helix, 25% strand	Q9V6K1

Pockets

18 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	958	0.81	0.83	111	empty
2	258	0.79	0.92	40	empty
3	512	0.77	0.84	57	empty
4	213	0.65	0.84	29	empty
5	268	0.60	0.79	28	empty

Compared structures

3LXU · Crystal Structure of Tripeptidyl Peptidase 2 (TPP II) · an experimental structure of the same protein · chain A against X, TM-score 0.83
3LXU · Crystal structure of tripeptidyl peptidase 2 (tpp II) · an experimental structure of the same protein · chain A against X, TM-score 0.83

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9V6K1
Elsewhere: UniProt Q9V6K1 · AlphaFold DB Q9V6K1

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